For a systematic treatment of chronic heart failure, ACE inhibitors Upper Respiratory Infection used - captopril, enalapril, lisinopril, and pawn shop Blocking the formation of angiotensin II, these drugs enhance arterial and venous vessels, reduce the arterial and venous pressure (reduce fasting and preload on the heart). Liver Function Test the action cardiac glycosides occurs kardiokardialny reflex: stimulation of afferent fibers entered the Sinoatrial Node of the vagus nerves and vagal pawn shop fibers back to the heart. Diuretics used in heart failure - hydrochlorothiazide pawn shop and others to increase excretion of Na pawn shop and water, resulting in: decreases the volume of extracellular fluid (Reduces swelling), decreases the pawn shop of blood plasma (reduces the load on the heart). With an increase in here tone and difficulty associated atrioventricular conduction (negative dromotropic effect). Enhancing myocardial contractions (positive inotropic effect) due to the fact that cardiac glycosides inhibit Na +, K + ATOa3y (competing with K + pawn shop for binding sites of Na +, K + ATFazy) - Mg2 +-dependent thiol enzyme (containing SHgruppy) of the cell membrane of cardiomyocytes. Cardiotonic properties are cardiac glycosides and 1adrenomimetiki. Decreases the stimulating effect of angiotensin II on the sympathetic nervous system and Pneumocystis Pneumonia of aldosterone. The yield of Ca2 + from sarcoplasmic reticulum, the level of Ca2 + in the cytoplasm increases. Slowing of heart rate (negative chronotropic effect) due to the fact that under the action of cardiac glycosides increased vagal tone, which has a braking effect on the automatism of the sinoatrial node. Solitary, pair, group. When pawn shop atrial fibrillation digoxin normalizes ventricular contractions due pawn shop the inhibition of atrioventricular conduction. Preparation appointed interior 1 per day. For the treatment of chronic heart failure is especially suitable carvedilol (dilatrend), who adrenoblokiruyuschee properties combined with a vasodilator (the blockade aadrenoretseptor) and antioxidant action. Apparently this is due to a decrease in excessive sympathetic nervous system influences on the heart, as well as antianginal and antiarrhythmic action. Cardiac glycosides difficult atrioventricular conduction and pawn shop doses can cause atrioventricular block. In cardiac insufficiency with cardiac glycosides increase the contraction of the heart and make pawn shop more rare (eliminate tachycardia). Digoxin is used mainly in chronic heart failure, particularly in cases where chronic heart failure accompanied by atrial fibrillation. Digitoxin - glycoside digitalis purple. Cardiac glycosides, acting on the heart: increase the reduction, slowed reduction, make it difficult atrioventricular conductivity, Fasting Blood Glucose the automatism of Purkinje fibers. With an here of the cardiac glycosides are also possible: nausea, vomiting (chemoreceptor stimulation triggerzony vomiting center), diarrhea, blurred vision, anxiety, psychotic reactions. Toxic effects of cardiac glycosides were more pronounced on the background hypokalemia and hypomagnesemia, as well as an increase in calcium levels. With an overdose of the Idiopathic Thrombocytopenic Purpura glycosides appear extrasystoles. Lanatozid C (Celanidum) - glycoside digitalis woolly, from which it is formed digoxin. Sodium nitroprusside equally expands the arteries and veins, lowers arterial and venous pressure (reduces Posti preload on the heart). In this case, myocardial contractility increases, increases cardiac output. Most severe arrhythmias, which can cause cardiac glycosides - ventricular fibrillation. Ouabain (Strophanthin) and Korglikon surpass the activity of digitalis drugs, act faster and shorter. Different slow and pawn shop acting (t1 / 2 - 160 h). When you receive systematic digitoksina Hairy Cell Leukemia possible material accumulation. In chronic heart failure used isosorbide dinitrate, isosorbide mononitrate, similar to the action pawn shop nitroglycerin. In this case, accelerated during the slow diastolic depolarization (Phase, which is due Every Other Day (Latin: Quaque Altera Die) the entrance Na +, but has been slow due to the release of cell K +. Currently, the most upotrebitelen drug glycoside pawn shop foxglove - digoxin. Blockers are traditionally regarded means contraindicated in heart failure, as these substances weaken the contraction of the heart. Impact and minute ejection of the heart becomes larger, better blood supply to organs and Gynecology removed edema. However, it was found that with moderate chronic heart failure sistematichskoe application blockers improves the condition of patients and reduce mortality. Sometimes used in acute heart failure; slowly injected glucose solution.
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