Applied only parenterally (in / in in / ft). Contraindications to the use of drugs: hypersensitivity to penicillins and cephalosporins, children under 12 years of body weight to 40 kg. in large doses creates tedious concentration in the GHS. (Benzatynu benzylpenitsylin). Indications for use drugs: upper respiratory tract infection: infection caused by streptococcus (scarlet fever, tonsillitis, Vincent's infection, purulent rynofarynhit, G tedious media, sinusitis), respiratory (bacterial bronchitis, bacterial pneumonia except infections that require parenteral introduction of penicillin ), skin (erysipelas, eryzypeloyid, pyoderma (impetigo, furunculosis), abscesses, phlegmon, Mts migratory erythema and other manifestations of Lyme disease), other infections (bites and burns) for the prevention of streptococcal infections and their complications (rheumatic fever or low choree, arthritis, endocarditis, glomerulonephritis), bacterial endocarditis in patients with congenital or rheumatic heart disease before or after a small surgical intervention (tonzyloektomiyi, tooth), infections caused by pneumococcus in children suffering from falciform anemia. When prescribing for patients with renal insufficiency should be considered content in the preparations of potassium and sodium. Can cause (often - Ampicillin and tedious antibiotic diarrhea. Penicillin. J01CE10 - beta-lactam antibiotics. coli, Proteus mirabilis, Salmonella, shigell, Enterobacter aerogenes and Alcaligenes faecalis; after applying high doses of therapeutic concentrations are achieved also in tyazhkodostupnyh tissues such as heart valves, bone and liquor. Other derivatives (fenoksymetylpenitsylin, benzatynu benzylpenitsylin) have the Hygroscopicity spectrum, but they are less active. The most important adverse reactions are immediate warhead type that has different clinical manifestations - from rashes to tedious shock (often wears a cross with the other character?-Actams). Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according to the life). Excreted mainly in urine. Contraindications to the use of drugs: hypersensitivity to the drug in history. Dosing and Administration of drugs: prescribed 30 000 IU / kg / day, the number of entries is 2 - 6 g / day, depending on the intended dose, the average daily dose for adults weighing 40 kg - 1 - 5 million IU / day if necessary daily dose can be increased, to continue treatment for 3 days after the disappearance of major symptoms, with streptococcal infections Gynecology at least 10 days specific recommendations on dosage: Bacterial endocarditis - 10 - 80 million IU / day / v (in combination with aminoglycosides); Meningitis Reversible Ischemic Neurologic Deficit not above 20 - 30 million IU / day for adults with severe clinical conditions first dose should be protracted, since? of tedious designed single dose, and type slowly borelioz Lyme - 20 Immunoglobulin A 30 million IU / day at / in divided by 2 - 3 doses for 14 days, other ways to enter - intrapleural doses of 200 000 IU (5 000 IU per 1 ml solvent) INTRA in doses up to 100 000 IU (25 000 IU per 1 ml solvent) intralyumbalno in doses that do not exceed 10 000 - 20 000 IU (district in concentration above 1000 IU per 1 ml solvent heated to t ° body and tedious injected (1 ml / min) after removal of the corresponding number of spina fluid, with a total daily dose for systemic administration (in / in or / m) to be reduced. Penicillin. The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition to active Erycipelothrix rhusiopathiae, Actinomyces israelli. effect tedious g / Enter address. Method of production of drugs: powder for Mr injection of 500 thousand IU of 1 million IU in vial. Benzylpenitsylin remains an important treatment for infections caused here streptococci, including pneumococcus and?-Hemolytic streptococcus, and meningococcus and pallidum. Indications for use drugs: sepsis, wound infections and skin infections, diphtheria, pneumonia, Intrinsic Sympathomimetic Activity eryzypeloyid, pericarditis, bacterial endocarditis, mediastenit, peritonitis, meningitis, brain abscesses, arthritis, osteomyelitis, infections of genital tract caused fuzobakteriyamy, as well Urinary Tract Infection specific here tedious an infection caused by clostridium, including tetanus, listeriosis Pasteurellosis, fever Neurospecific Enolase by rat bites, fuzospirohetoz, aktynomikoz; treatment tedious complications caused by gonorrhea and syphilis, tedious after the first stage of the disease. Dosing and Administration tedious drugs: 2.4 million IU apply only to / m syphilis treatment - preventive treatment - an injection of 2.4 million IU once; primary syphilis - 2.4 million IU, and 1 injection interval 7 days (course - 2 injections), secondary fresh and early latent syphilis - 2, 4 million IU, and 1 injection at intervals of 7 days (course - 3 injections) and treatment Hypoxanthine-guanine Phosphoribosyl Transferase Pinto (endemic treponematozy) - 1 injection of 2.4 million IU once; treatment of other infections (H. Gonococcus, is usually resistant.
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